CASE OF THE DAY RESULTS

CASE #1:

Contributed by Dr. Andrew Evans, University Health Network, Toronto, Canada

Clinical History: A 49 year-old man underwent ten core needle prostate biopsies. Normal prostate by digital examination, no urinary symptoms, PSA was 4.2 having risen from 2.5 six months previously. One prostate core showed an isolated finding.

Possible diagnoses:
  • Benign/atrophic glands
  • Atypical small acini (ASAP)
  • High grade prostatic intraepithelial neoplasia (PIN)
  • Microfocal invasive adenocarcinoma, Gleason score 6/10 (3+3)
To view additional details and case information, click here

Special thanks to the Canadian Association of Pathologists and Doug Tkachuk, Objective Pathology Ltd. for their contributions to Aperio’s “Case of the Day”.

CASE #2:

Contributed by Dr. Runjan Chetty, University Health Network, Toronto, Canada.

Please select a diagnosis:
  • Hyperplastic polyp
  • Inflammatory polyp
  • Tubular adenoma
  • Sessile serrated adenoma
  • Tubulovillous adenoma
  • Tubulovillous adenoma with focal high-grade dysplasia
  • Invasive adenocarcinoma
CASE #3:

Contributed by: Dr. Shitabata, Pathology Inc.

Clinical History: 37 year old man with painful tumor arising in the right arm.  Classic painful tumors of the skin include Neuroma, Angiolipoma, Leiomyoma, and Glomus tumor.

Possible diagnoses:
  • Eccrine spiradenoma
  • Glomus tumor
  • Basal cell carcinoma
  • Trichoblastoma
Special thanks to Dr. Eric Glassy, Pathology Inc. for his contributions to Aperio’s “Case of the Day”.

CASE #4:

Contributed by: Dr. Shitabata, Pathology Inc.

Clinical History: 25 year old man with flesh colored tumor on the chest wall.

Possible diagnoses:
  • Granular cell tumor
  • Langherhans cell histiocytosis
  • Dermatofibroma
  • Extra-renal rhabdoid tumor
Special thanks to Dr. Eric Glassy, Pathology Inc. for his contributions to Aperio’s “Case of the Day”.

CASE #5:

Contributed by: Dr. Shitabata, Pathology Inc.

Clinical History: 46 year old Filipino woman who presents with multiple suspicious calcifications on mammogram.

Possible diagnoses:
  • Collagenous spherulosis
  • Mondor’s disease
  • Parasite
  • Post-irradiation change
  • Implant reaction
Special thanks to Dr. Eric Glassy, Pathology Inc. for his contributions to Aperio’s “Case of the Day”.

CASE #6:

Contributed by Dr. William Geddie, University Health Network, Toronto, Canada (william.geddie@uhn.on.ca).

Clinical History: A 19-year-old woman presents with unilateral cervical lymphadenopathy. An FNA is performed of the left level-4 lymph node.

Possible diagnoses:
  • Normal lymph node tissue
  • Metastatic carcinoma
  • Suspicious for large cell lymphoma
  • Suspicious for low grade lymphoproliferative disorder
  • Hodgkin Lymphoma
Special thanks to the Canadian Association of Pathologists and Doug Tkachuk, Objective Pathology Ltd. for their contributions to Aperio’s “Case of the Day”.


* Aperio products are FDA cleared for specific clinical applications, and are intended for research use for other applications.